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Author contributions: R.J.R., A.S.G., and F.M.W. designed research; R.J.R., A.S.G., E.J.S., and T.G.C. performed research; R.J.R., A.S.G., D.A.R., and F.M.W. analyzed data; and R.J.R., A.S.G., and F.M.W.